Title: Effects of Thoracic Epidural Analgesia on Plasma Camp and Cgmp Levels in Patients with Heart Failure

Introduction introduction needs to be expanded with more emphasis on the relevance of epidural anaesthesia to heart failure with support of literature. At present there is only one self citation. Methods – Please do not mention the type of NYHA class the patients were before starting treatment. This suggests randomization was not properly done. Mention them in the result section. Why lidocaine was used only during the daytime? Provide some justification in the discussion. How did u confirm that epidural catheter tip was in the T1-2 level, by any contrast study or ultrasound etc? Please mention. Results: please refer to the tables and figures in the text. U can include a table showing the NYHA status of patients before and after treatment in both the groups. Discussion: well structured. Why lidocaine was used only during the daytime? Provide some justification in the discussion. What is the ideal level of epidural catheter tip for adequate sympathetic blockade of heart? Mention with some reference.